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Home » Recipes » Recipes

Bison Cheesesteak Sandwich

Modified: Nov 13, 2025 · Published: Apr 16, 2022 by Kay Schrock · This post may contain affiliate links · Leave a Comment

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When you put tender bison steak strips, silky sautéed onions, and melted cheese together - all tucked into a buttery, toasted roll, you get this bison cheesesteak sandwich! 

Recently, I was approached by Blackstone products about a cheesesteak collaboration. I was happy to join in the fun and create a sandwich to represent our state. Wyoming is is known for its herds of bison ( locals call them buffalo), and I decided to go with the state theme and throw some in a recipe. So, I picked up these bison sirloin steaks and had fun creating this delicious cheesesteak sandwich. I enjoyed it so much - I might just have to make some more bison recipes!

Bison Cheesesteak Sandwiches on a plate

How to make Bison Cheesesteak Sandwich

First, place the steaks in the freezer for 30 minutes to get really chilled. This makes it easier to slice it thin. If you are using already frozen meat, then let it thaw in the fridge overnight so it is still firm and partially frozen when you slice it. 

raw bison steak in packaging

Next, slice up a large onion. I like thick slices, but you can slice or dice according to your preference. 

Prep the meat

Then, slice up that meat. Slice across the grain and make the slices as thin as you can. I like to try for about 1/8th of an inch thick, but just do the best you can The important thing, is that you make them uniform in size, so they cook evenly.

bison steak sliced thin on cutting board

Sauté the onions

Now, heat a cast iron skillet over medium heat and add oil. (you can use any heavy skillet) Fry the onions till they are soft and beginning to turn golden brown on the edges. Stir them often while frying. When the onions are done, put them on a plate and set aside. 

Fry the bison meat

Add some more oil to the pan and turn to med-high heat. Add the bison meat. Spread it out as evenly as possible. Fry the meat quickly to desired doneness. I like to fry mine quickly on both sides, just until the pink is mostly gone but the juices haven't fried off yet. This makes a very tender sandwich, easy to bite and chew. If you try to get a dark seared look, it may get too tough. 

bison steak frying in pan

bison steak in skillet with sautéed onion

Add cheese and seasonings

Remove pan from heat. Season with some Cavender's greek seasoning. Stir the onions back into the meat, and cover the meat with slices of cheese. Cover skillet with a large lid or piece of foil, and let it sit for 2 minutes to allow the cheese to melt.

slices of cheese on meat in skillet

pepper jack cheese melting over bison meat in skillet

Toast the rolls

While cheese is melting, heat a griddle or other large skillet over med-high heat. Slice 4 hoagie rolls and butter generously. Toast the rolls on the griddle. This is an optional step but really adds a layer off flavor and texture that sets this bison cheesesteak sandwich apart! 

Assemble sanwiches

When the rolls are toasted, the cheese is melted, you are ready for the big moment! Divide that meat mixture into 4 equal parts and place it in the hot rolls. Serve warm to people you love! 

bison cheesesteak sandwiches on plate

Where to buy  bison steak? 

I found some at my local grocery store. (Safeway) But, I am in Wyoming where we raise bison! If you can't find it in a store, you may need to order online. 

Free Cheesesteak Recipe book

My bison recipe is in the Blackstone free ebook - be sure to grab your copy! Try several of the recipes and share on your social media channel with the hashtag #freethecheesesteak!

bison cheesesteak sandwiches on plate

Bison Cheesesteak Sandwich

Kay Schrock
This Bison Cheesesteak Sandwich is savory, tender, and succulent! It combines healthy bison meat with creamy pepper jack for a delectable sandwich.
2 from 2 votes
Print Recipe Pin Recipe
Prep Time 30 minutes mins
Cook Time 10 minutes mins
Total Time 40 minutes mins
Course Main
Cuisine American
Servings 4 sandwiches
Calories 507 kcal

Ingredients
  

  • 1 lb bison sirloin steak
  • 1 large onion sliced
  • 4 French Steak rolls or hoagie rolls
  • 2 Tablespoons olive oil
  • ½ tsp Cavender's all-purpose greek seasoning
  • 4 slices pepper jack cheese
  • 2 Tablespoons butter

Instructions
 

  • Place the steaks in the freezer for 30 minutes to chill thoroughly.  
  • Slice the onion into thick slices. 
  • Remove the bison steak from the freezer, and slice into very thin slices. 
  • Heat a cast iron skillet over medium heat and add 1 Tablespoon olive oil. When the oil is hot, add the onions and stir them till soft and beginning to turn brown. When the onions are done, put them on a plate and set aside. 
  • Add some more oil to the pan and turn to med-high heat. Add the bison meat. Spread it out as evenly as possible. Fry the meat quickly on both sides, just until the pink is mostly gone but the juices haven't fried off.
  • Season with Cavender's greek seasoning. Stir the onions back into the meat, and cover the meat with slices of cheese. Remove skillet from heat and cover skillet with a large lid or piece of foil, and let it sit for 2 minutes to allow the cheese to melt.
  • While cheese is melting, heat a griddle or other large skillet over med-high heat. Slice 4 rolls and butter generously. Toast the rolls on the griddle. Divide the meat mixture into 4 equal parts and place it in the hot rolls. Serve warm.

Nutrition

Serving: 1gCalories: 507kcalCarbohydrates: 36gProtein: 35gFat: 24gSaturated Fat: 10gPolyunsaturated Fat: 1gMonounsaturated Fat: 10gTrans Fat: 1gCholesterol: 114mgSodium: 515mgPotassium: 453mgFiber: 2gSugar: 6gVitamin A: 341IUVitamin C: 3mgCalcium: 179mgIron: 14mg
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Welcome!

I am Kay, a mom, homeschooler, Wyoming gal, and disciple of Jesus. I was raised by an Amish mother who was a great cook, baker, and homemaker. I learned to cook like her: comfort food from scratch.

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